Table 2.
Descriptive statistics and summary of group comparisons for the psychosocial variables
| Scale | Scale range / threshold | Overall | BRCA1 mutation carriers | BRCA2 mutation carriers | Controls | Cohen's d * | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| N | Mean (sd) % above threshold | N | Mean (sd) % above threshold | N | Mean (sd) % above threshold | N | Mean (sd) % above threshold | ||||
| SF‐36 physical component summary | Range | 0–100 | 404 | 47.4 (10.0) | 90 | 46.4 (10.7) | 148 | 47.1 (10.1) | 166 | 48.3 (8.6) | |
| SF‐36 mental component summary | Range | 0–100 | 404 | 52.4 (10.2) | 90 | 52.1 (11.1) | 148 | 51.2 (10.5) | 166 | 53.7 (9.3) | |
| Total anxiety (HADS) | Range | 0–21 | 431 | 4.9 (3.6) | 97 | 4.9 (3.5) | 160 | 4.8 (3.8) | 174 | 4.9 (3.4) | |
| Abnormal threshold | ≥11 | 28 | 6.5% | 6 | 6.2% | 12 | 7.5% | 10 | 5.7% | ||
| Total depression (HADS) | Range | 0–21 | 431 | 2.8 (3.0) | 97 | 2.9 (3.2) | 160 | 2.9 (3.1) | 174 | 2.7 (2.7) | |
| Abnormal threshold | ≥11 | 9 | 2.1% | 3 | 3.1% | 4 | 2.5% | 2 | 1.1% | ||
| Total intrusion (IES) | Range | 0–35 | 423 | 2.3 (4.9) | 94 | 3.0 † (5.7) | 158 | 3.1 † (5.5) | 171 | 1.3 † (3.5) | −0.02; 0.35; 0.38 |
| Abnormal threshold | ≥19 | 12 | 2.8% | 4 | 4.3% | 6 | 3.8% | 2 | 1.2% | ||
| Total avoidance (IES) | Range | 0–40 | 418 | 4.3 (7.0) | 93 | 6.0 † (8.4) | 156 | 5.1 † (7.4) | 169 | 2.6 † (5.2) | 0.11; 0.48; 0.39 |
| Abnormal threshold | ≥19 | 32 | 7.7% | 12 | 12.9% | 15 | 9.6% | 5 | 3.0% | ||
| Total MAX‐PC | Range | 0‐33 | 420 | 3.5 (5.4) | 94 | 4.1 (5.5) | 156 | 3.9 (6.2) | 170 | 2.8 (4.6) | |
| Total cancer worry | Range | 4–24 | 430 | 9.5 (2.5) | 97 | 9.7 † (2.7) | 160 | 9.9 † (2.7) | 173 | 9.1 † (2.0) | −0.09; 0.25; 0.36 |
| Risk perception | 423 | N/A | 91 | N/A | 156 | N/A | 171 | N/A | |||
| Moderately or strongly increased | 133 | 31.4% | 31 | 32.3% ‡ | 86 | 55.1% ‡ | 16 | 9.4% ‡ | 0.43§ | ||
| Total knowledge score | Range | 0–9 | 404 | 7.1 (1.7) | 92 | 6.9 (1.8) | 151 | 7.2 (1.6) | 161 | 7.1 (1.7) | |
HADS, Hospital Anxiety and Depression Scale; IES, Impact of Event Scale; MAX‐PC, Memorial Anxiety Scale for Prostate Cancer; SF‐36, 36‐item short‐form health survey. *Cohen's d values are listed comparing BRCA1 mutation carriers with BRCA2 mutation carriers; BRCA1 mutation carriers with controls; BRCA2 mutation carriers with controls. † P < 0.01 using ANOVA. † P < 0.01 using a chi‐squared test for independence. §Cramer's V test for nominal association. Bold font indicates statistically significant values.