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. 2019 Feb 18;26:20. doi: 10.1186/s12929-019-0510-4

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Increased expression of DNA repair and DNA damage response genes in ESCC radio-resistant cell line. a RT-qPCR showed that KYSE510 radio-resistant cells (KYSE510R) exhibited significantly higher basal expression levels of DNA repair genes (upper) and DNA damage response genes (lower) in comparison with KYSE510 parental cells. Data represent mean ± S.D. P-values were determined by two-tailed Student’s t-test. *P < 0.05; **P < 0.01. b The protein expression level of DNA repair proteins and DNA damage response proteins in KYSE510-R was higher than that in KYSE510 cells. β-actin was used as an internal control for western blots