Table 5.
Inhibition of the proinflammatory enzymes.
Analyte | LOX | HYAL | ||
---|---|---|---|---|
IC50 (μg/mL)∗ | IC50 (μg/U)∗∗ | IC50 (μg/mL)∗ | IC50 (μg/U)∗∗ | |
MED | 188.1 ± 6.8e | 6.94 | 18.3 ± 0.7f | 16.0 |
DEF | 91.6 ± 3.6b | 3.38 | 25.3 ± 0.9h | 22.2 |
EAF | 89.8 ± 4.3b | 3.31 | 12.4 ± 0.5c | 10.9 |
BF | 96.3 ± 3.7b,c | 3.55 | 4.1 ± 0.2a | 3.62 |
WR | 265.3 ± 7.2f | 9.79 | 11.3 ± 0.5c | 9.94 |
QU | 58.3 ± 2.3a | 2.15 | 15.6 ± 0.9d,e | 13.7 |
RT | 104.8 ± 4.1c | 3.86 | 23.2 ± 1.6g | 20.4 |
CHA | 114.3 ± 5.2d | 4.21 | 16.5 ± 0.7e | 14.5 |
ECA | 90.6 ± 3.1b | 3.34 | 14.3 ± 0.7d | 12.5 |
PB2 | 77.0 ± 1.8b | 2.84 | 12.8 ± 0.6d | 11.2 |
IND | 63.0 ± 2.7a | 2.32 | 8.5 ± 0.4b | 7.46 |
Results are presented as means ± SD (n = 3) calculated per dry weight of the extract or standard. For extract codes, see Table 1. Different superscripts in each column indicate significant differences in the means at p < 0.05. ∗,∗∗Inhibition concentration (amount of analyte needed for 50% inhibition of enzyme activity) expressed as follows: ∗in μg of the dry extract or standard/mL of the enzyme solution; ∗∗in μg of the extracts/enzyme unit (U).