Table 2.
CXCR2 genotype and allele frequencies in CP patients and healthy nonperiodontitis controls.
| Genotypes | Controls | CP | P value | OR (95% CI) |
|---|---|---|---|---|
| Alleles | N = 171 (%) | N = 329 (%) | ||
| CXCR2 +785 | ||||
| CC | 41 (24.0) | 81 (24.6) | — | 1.00 |
| CT | 93 (54.4) | 166 (50.5) | 0.37 | 0.90 (0.57-1.42) |
| TT | 37 (21.6) | 82 (24.9) | 0.39 | 1.12 (0.65-1.93) |
| C allele | 175 (51.2) | 328 (49.8) | — | 1.00 |
| T allele | 167 (48.8) | 330 (50.2) | 0.37 | 1.05 (0.81-1.37) |
|
| ||||
| CXCR2 +1208 | ||||
| CC | 45 (26.3) | 91 (27.7) | — | 1.00 |
| CT | 90 (52.6) | 174 (52.9) | 0.47 | 0.96 (0.62-1.48) |
| TT | 36 (21.1) | 64 (19.5) | 0.37 | 0.88 (0.51-1.51) |
| C allele | 180 (52.6) | 356 (54.1) | — | 1.00 |
| T allele | 162 (47.4) | 302 (45.9) | 0.35 | 0.94 (0.73-1.22) |
|
| ||||
| CXCR2 +1440 | ||||
| AA | 35 (20.5) | 59 (17.9) | — | 1.00 |
| AG | 89 (52.0) | 171 (52.0) | 0.34 | 1.14 (0.70-1.86) |
| GG | 47 (27.5) | 99 (30.1) | 0.25 | 1.25 (0.73-2.15) |
| A allele | 159 (46.5) | 289 (43.9) | — | 1.00 |
| G allele | 183 (53.5) | 369 (56.1) | 0.24 | 1.11 (0.85-1.44) |
CI = confidential interval; CP = chronic periodontitis; N = number of subjects; OR = odds ratio.