Table 4.
Percent change in gene expression in the L2/L3 DRGs of GHRHr−/− mice relative to WT at P7, P14 and P21. *p < 0.05, one-way ANOVA with Tukey’s post hoc test. ^data analyzed with Kruskal Wallis and Dunn’s post hoc tests.
| Gene | IGFr1 | ASIC3 | P2X3 | Piezo 2 | TRPV1 | TRPM3 | P2Y1 | GFRα1 | GFRα3 | trkA | Esr1 | Esr2 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P7 | 208 ± 9%* | 21 ± 20% | 6 ± 31% | −5 ± 21% | 14 ± 19% | −4 ± 22% | −17 ± 17% | −16 ± 31% | 52 ± 22% | 50 ± 34% | 368 ± 9%* | 597 ± 26%* |
| P14 | 277 ± 12%* | 450 ± 51%* | 968 ± 21%* | 252 ± 16%* | 1529 ± 23%* | 323 ± 21%* | 41 ± 8%* | 5 ± 57% | 4673 ± 55%*,^ | 2686 ± 47%*,^ | −17 ± 22% | −51 ± 34% |
| P21 | 33 ± 28% | 9 ± 19% | 191 ± 10%* | 145 ± 11%* | 209 ± 10%* | 60 ± 23% | 168 ± 12%* | 155 ± 22%* | 57 ± 14% | 195 ± 6%* | −11 ± 21% | 65 ± 51% |