Table 3.
Comparison of DHI, postural stability and sensory integration between the ASIC3 genetic variants.
| DHI-physical | DHI-emotion | DHI-function | Balance—stability -Overall | Balance—stability anterior-to-posterior | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| mTBI | Control | mTBI | Control | mTBI | Control | mTBI | Control | mTBI | Control | ||
| rs2288645 | AA&AG | 11.39 ± 8.42* | 2.76 ± 3.87 | 8.74 ± 9.25 | 2.24 ± 5.41 | 13.47 ± 11.52 | 2.81 ± 5.25 | 0.49 ± 0.26 | 0.50 ± 0.22 | 0.38 ± 0.20 | 0.37 ± 0.20* |
| GG | 8.76 ± 7.87 | 4.09 ± 0.71 | 8.40 ± 7.81 | 3.16 ± 6.31 | 11.65 ± 10.66 | 4.93 ± 8.73 | 0.50 ± 0.29 | 0.45 ± 0.28 | 0.39 ± 0.25 | 0.33 ± 0.26 | |
| rs2288646 | AG | 13.09 ± 9.97 | 1.33 ± 3.23 | 9.64 ± 9.79 | 0.5 ± 1.73 | 15.45 ± 13.92 | 1.33 ± 3.23 | 0.48 ± 0.29 | 0.57 ± 0.31 | 0.35 ± 0.20 | 0.39 ± 0.27 |
| GG | 9.57 ± 8.03 | 3.86 ± 4.49 | 8.47 ± 8.30 | 3.09 ± 6.25 | 12.16 ± 10.83 | 4.45 ± 7.95 | 0.50 ± 0.28 | 0.45 ± 0.25 | 0.38 ± 0.24 | 0.34 ± 0.23 | |
| rs4148855 | (–/–)&(–/GTC) | 9.47 ± 8.12 | 3.6 ± 4.56 | 8.26 ± 8.13 | 3.42 ± 8.01 | 11.65 ± 10.56 | 3.91 ± 8.23 | 0.53 ± 0.33 | 0.49 ± 0.35 | 0.41 ± 0.28 | 0.36 ± 0.33 |
| (GTC/GTC) | 10.11 ± 8.24 | 3.56 ± 4.37 | 8.86 ± 8.67 | 2.38 ± 3.98 | 13.16 ± 11.51 | 4.25 ± 7.23 | 0.46 ± 0.20 | 0.45 ± 0.16 | 0.35 ± 0.16 | 0.34 ± 0.15 | |
| Balance—stability medial-to lateral | Sensory integration-EOFI | Sensory integration-ECFI | Sensory integration-EOFO | Sensory integration-ECFO | |||||||
| mTBI | Control | mTBI | Control | mTBI | Control | mTBI | Control | mTBI | Control | ||
| rs2288645 | AA&AG | 0.21 ± 0.15 | 0.24 ± 0.13 | 0.52 ± 0.22 | 0.52 ± 0.22 | 1.07 ± 0.48 | 1.27 ± 0.76 | 0.92 ± 0.36 | 0.79 ± 0.21 | 3.06 ± 1.12 | 2.71 ± 0.98 |
| GG | 0.21 ± 0.14 | 0.21 ± 0.10 | 0.53 ± 0.28 | 0.52 ± 0.36 | 1.16 ± 0.60 | 1.29 ± 0.83 | 0.97 ± 0.56 | 0.77 ± 0.23 | 3.25 ± 1.37 | 2.46 ± 0.97 | |
| rs2288646 | AG | 0.23 ± 0.17 | 0.31 ± 0.17* | 0.50 ± 0.30 | 0.58 ± 0.17 | 0.94 ± 0.34 | 1.33 ± 0.50 | 0.89 ± 0.18 | 0.84 ± 0.20 | 3.02 ± 1.07 | 2.72 ± 0.74 |
| GG | 0.21 ± 0.14 | 0.21 ± 0.10 | 0.53 ± 0.26 | 0.51 ± 0.33 | 1.14 ± 0.56 | 1.28 ± 0.83 | 0.95 ± 0.51 | 0.77 ± 0.22 | 3.19 ± 1.30 | 2.54 ± 1.00 | |
| rs4148855 | (–/–)&(–/GTC) | 0.22 ± 0.16 | 0.24 ± 0.13 | 0.55 ± 0.30 | 0.56 ± 0.42 | 1.10 ± 0.56 | 1.42 ± 0.95 | 1.00 ± 0.58 | 0.77 ± 0.25 | 3.27 ± 1.38 | 2.56 ± 1.00 |
| (GTC/GTC) | 0.20 ± 0.12 | 0.21 ± 0.10 | 0.50 ± 0.19 | 0.50 ± 0.20 | 1.16 ± 0.55 | 1.18 ± 0.67 | 0.89 ± 0.38 | 0.78 ± 0.20 | 3.07 ± 1.16 | 2.56 ± 0.96 | |
DHI, Dizziness Handicap Inventory; EOFI, eyes open while standing on a firm surface; ECFI, eyes closed while standing on a firm surface; EOFO, eyes open while standing on an unstable (foam) surface; ECFO, eyes closed while standing on an unstable (foam) surface,
*
indicates p < 0.05; The data were presented by (mean ± standard deviation).