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. 2019 Feb 16;5(2):e01231. doi: 10.1016/j.heliyon.2019.e01231

Table 4.

The histological features of the liver biopsy specimens from patients who underwent a blood test to measure the plasma L59/LAP-DP concentration.

Grade/Stage CHB (n) CHC (n) P-valuea
Inflammation
 A0 (no activity) 1 3
 A1 (mild activity) 6 19 <0.05
 A2 (moderate activity) 10 8
 A3 (severe activity) 2 0
Fibrosis
 F0 (no fibrosis) 1 3
 F1 (portal fibrosis w/o septa) 7 16
 F2 (portal fibrosis with few septa) 9 8 0.63
 F3 (numerous septa w/o cirrhosis) 1 2
 F4 (cirrhosis) 1 1

CHB, chronic hepatitis B; CHC, chronic hepatitis C; w/o, without.

a

The difference in the distribution of the grades of inflammation or the stages of fibrosis between the two patient groups (CHB versus CHC) was statistically analyzed with a chi-squared test.