Table 2.
Spatiotemporal and host features of European brown hare tularemia cases per Francisella tularensis subspecies holartica genotype.
| Basal clade | Subclade | Month/year of infection | Location (province) | No. of cases | Age category§ | Sex$ | Body condition& |
|---|---|---|---|---|---|---|---|
| B.6 | B.11 | May 2013 | Limburg | 1 | A | M | G |
| B.6 | NT | June 2015 | Gelderland | 1 | A | M | M |
| B.6 | NT | March 2016 | Groningen | 1 | A | M | P |
| B.6 | NT | May 2016, Oct-Nov 2016, Mar 2017, May 2017 | Utrecht | 8*# | 5A, 1I | 3M, 2F | 3G, 1M, 2P |
| B.6 | NT | Nov 2017 | Limburg | 1 | I | F | Moderate |
| B.12 | B.20a | Jan 2014 | Zeeland | 1** | |||
| B.12 | B.20a | April 2014 | Utrecht | 1 | A | M | M |
| B.12 | B.20a | Feb-May 2015 | Friesland | 11 | 8A, 1I | 9M, 2F | 2G, 7M, 2P |
| B.12 | B.20a | March 2015 | Friesland | 1# | |||
| B.12 | B.20a | March 2015 | Overijssel | 1 | A | M | G |
| B.12 | NT | Jan 2016 | Friesland | 1 | A | M | M |
| B.12 | NT | Oct 2016 | South Holland | 1 | I | M | M |
| 2 clades | 5 years | 8 provinces | 29 cases |
One hare linked to a human case. Pathological examination not possible on this specimen because it had been eviscerated and skinned.
Hare linked to a human case. Pathological examination not possible on this specimen because it had been eviscerated and skinned. Genotype (determined in muscle tissue) identical to that in the human patient linked to this case.
One hare too autolytic for pathological examination.
Age category (when determined): A, Adult; I, Immature.
Sex (when determined): M, male; F, female.
Body condition (when determined): G, good; M, moderate; P, poor.
The clade is denoted B.20 since the first canSNP used for this branch was B.20. In this study, B.42 was used for typing which is another canSNP along the same branch.