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. 2018 Nov 1;2018(11):CD011905. doi: 10.1002/14651858.CD011905.pub2

NCT02185222.

Trial name or title Effect of vitamin D on cognitive decline of patients with memory complaint (trial short name = D‐COG).
Methods RCT, triple‐blind.
Participants Aged 60+; both genders; "report to a memory centre with symptoms of memory complaint"; MMSE score "> the 5th percentile for sociocultural level of the patient", no dementia.
Interventions Experimental: Cholecalciferol 100 000 IU per month as a single dose, administered as oral solution. Control: placebo. Duration: 2 years.
Outcomes Primary outcome: change from baseline on total recall test from Free and Cued Selective Reminding Test.
Secondary outcomes: multiple general and domain‐specific cognitive tests; all adverse events; several biochemical outcomes.
Starting date July 2014
Contact information Sponsored by University Hospital, Tours. Contact fanny.hennekinne@univ‐tours.fr
Notes Estimated completion date July 2018.

MMSE: Mini‐mental state examination