NCT02185222.
Trial name or title | Effect of vitamin D on cognitive decline of patients with memory complaint (trial short name = D‐COG). |
Methods | RCT, triple‐blind. |
Participants | Aged 60+; both genders; "report to a memory centre with symptoms of memory complaint"; MMSE score "> the 5th percentile for sociocultural level of the patient", no dementia. |
Interventions | Experimental: Cholecalciferol 100 000 IU per month as a single dose, administered as oral solution. Control: placebo. Duration: 2 years. |
Outcomes | Primary outcome: change from baseline on total recall test from Free and Cued Selective Reminding Test. Secondary outcomes: multiple general and domain‐specific cognitive tests; all adverse events; several biochemical outcomes. |
Starting date | July 2014 |
Contact information | Sponsored by University Hospital, Tours. Contact fanny.hennekinne@univ‐tours.fr |
Notes | Estimated completion date July 2018. |
MMSE: Mini‐mental state examination