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. 2018 Dec 13;294(7):2375–2385. doi: 10.1074/jbc.RA118.006229

Table 1.

Protein constructs

Construct name ECD interface Substitutions
GABAAR β3-cryst β3(+)β3(−) Substitute ICD (346–396) for SQPARAA
GABAAR β3 C1 β3(+)α1(−) β3-cryst + Y87F,Q89R,G152T
GABAAR β3 C1 N66D β3(+)α1(−) C1 + N66D
GABAAR β3 C1 A70T β3(+)α1(−) C1 + A70T
GABAAR β3 C1 F87Y β3(+)α1(−) β3-cryst + Q89R,G152T