Table 2.
Summary of Hill slope, EC50, and current density values obtained for GABA activation of GABAAR β3 C1 and F87Y
Mean ± S.D. Hill slope and EC50 values obtained from logistic function fit parameters of individual experiments and mean ± S.D. current densities evoked by peak concentrations of GABA are shown. No significant differences between GABAAR β3 C1 and F87Y were observed (t test; EC50 p = 0.2; current densities p = 0.6). n = number of experiments.
Receptor | Hill slope | EC50 | Current density | n |
---|---|---|---|---|
mm | pA/pF | |||
GABAAR β3 C1 | 1.3 ± 0.4 | 2.9 ± 2.1 | −15.7 ± 12.5 | 4 |
GABAAR β3 C1 F87Y | 1.2 ± 0.3 | 1.3 ± 0.6 | −17.1 ± 11.9 | 4 |