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. 2018 Dec 13;294(7):2375–2385. doi: 10.1074/jbc.RA118.006229

Table 2.

Summary of Hill slope, EC50, and current density values obtained for GABA activation of GABAAR β3 C1 and F87Y

Mean ± S.D. Hill slope and EC50 values obtained from logistic function fit parameters of individual experiments and mean ± S.D. current densities evoked by peak concentrations of GABA are shown. No significant differences between GABAAR β3 C1 and F87Y were observed (t test; EC50 p = 0.2; current densities p = 0.6). n = number of experiments.

Receptor Hill slope EC50 Current density n
mm pA/pF
GABAAR β3 C1 1.3 ± 0.4 2.9 ± 2.1 −15.7 ± 12.5 4
GABAAR β3 C1 F87Y 1.2 ± 0.3 1.3 ± 0.6 −17.1 ± 11.9 4