. 2018 Dec 19;294(7):2486–2499. doi: 10.1074/jbc.RA118.006319

Table 1.

Periphery blood cytometry in mice exposed to benzene by inhalation and oral gavage

Exposure route	Exposure level (mean ± S.D., ppm or mg/kg)
Exposure route	0	1	10	100
Dynamic inhalation (n = 10)
WBC (10⁹/liter)	4.69 ± 0.79	4.01 ± 0.69^a	3.67 ± 0.62^a	1.68 ± 0.43^a
RBC (10¹²/liter)	7.43 ± 0.58	7.04 ± 1.16	6.97 ± 0.78	5.08 ± 0.84^a
Platelets (10⁹/liter)	1249.07 ± 124.90	1271.52 ± 188.36	1256.22 ± 83.59	1022.59 ± 134.67^a
LYM (10⁹/liter)	2.62 ± 0.39	2.00 ± 0.38^a	1.71 ± 0.45^a	0.81 ± 0.28^a
MCV (f l)	51.42 ± 2.22	52.89 ± 2.74	56.88 ± 3.6^a	57.45 ± 3.30^a

Oral gavage (n = 6)
WBC (10⁹/liter)	4.83 ± 0.97	4.10 ± 1.13	3.47 ± 0.85^a	1.73 ± 0.31^a
RBC (10¹²/liter)	7.15 ± 0.23	6.77 ± 0.47	6.72 ± 0.26	5.15 ± 0.69^a
Platelets (10⁹/liter)	1234.20 ± 81.71	1200.50 ± 70.44	1219.10 ± 86.55	1219.87 ± 108.16
LYM (10⁹/liter)	2.57 ± 0.63	1.76 ± 0.65^a	1.70 ± 0.70^a	0.77 ± 0.22^a
MCV (f l)	54.87 ± 1.68	52.66 ± 2.36	57.68 ± 1.51^a	58.18 ± 3.11^a

^a p < 0.05, compared with the corresponding control group, as determined by independent-sample t test or assessed with one-way ANOVA followed by Bonferroni post-test.