Skip to main content
. 2019 Feb 18;15(2):e8513. doi: 10.15252/msb.20188513

Figure EV4. PTR‐AI correlates with codon decoding time and codon effect on mRNA half‐life.

Figure EV4

  1. Median PTR‐AI across tissues negatively correlates with expected codon decoding times in 17 ribosome profiling datasets (O'Connor et al, 2016).
  2. Median PTR‐AI across tissues highly correlates with mRNA half‐life fold‐changes associated with twofold frequency increase of codons in K562 (Schwalb et al, 2016), HEK293 (Schueler et al, 2014), and HeLa Tet‐off cells (Tani et al, 2012).