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. Author manuscript; available in PMC: 2019 Feb 18.
Published in final edited form as: Biochemistry. 2016 Jul 13;55(29):4036–4046. doi: 10.1021/acs.biochem.6b00401

Figure 7. The Complete Interaction Scheme.

Figure 7.

The fourteen enzyme forms involved in the bindii and interactions of EGCG (G) and PAP (P) are shown. The enzyme symbol, E, is “sided” - the two right- and left-hand corners represent binding sites on separate subunits of the SULT1A1 dimer. Upper and lower corners represent the G- and P-binding sites, respectively. The 20 binding steps that interconvert the species are numbered, and the corresponding equilibrium constants can be found in Table S1. A blue letter indicates that that ligand is bound to a subunil whose cap is closed.