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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Clin Pharmacol Ther. 2018 Oct 18;105(3):703–709. doi: 10.1002/cpt.1233

Table 4:

Association between concurrent prescription of tizanidine and a CYP1A2 inhibitor and lowest systolic blood pressure

Beta coefficient 95% CI p-value
Beta coefficient (95% CI), unadjusted −1.61 −2.77, −0.44 0.007
Beta coefficient – adjusted for age, race, and sex −1.28 −2.46, −0.11 0.032
Beta coefficient-adjusted for logarithmically transformed PS* −0.92 −2.10, 0.26 0.127
*

PS included the following variables: age, use of ciprofloxacin vs fluvoxamine, race, sex, Charlson score, current use of ARBs, ACE inhibitors, beta-blockers, calcium channel blockers, diuretics, alpha-agonist agents, and other antihypertensive agents.