Table 1.

General functions of lymphoid-derived cells.

Cell Type	Antigen Specificity	SPM/ Eicosanoid Receptor Expression	Function
T helper Cell Type 1	⌷	ALX/FPR2, BLT1, ChemR23, EP2, EP4, GPR32	CD4+ effector cell against intracellular pathogens, autoimmunity, inflammation
T helper Cell Type 17	⌷	ALX/FPR2, BLT1, ChemR23, EP2, EP4, GPR32	CD4+ effector cell against extracellular pathogens, autoimmunity, inflammation
Cytotoxic T Lymphocyte	⌷	BLT1	CD8+ effector cell that kill cells infected with intracellular pathogens and cancer cells
T regulatory Cell	⌷	ALX/FPR2, EP2	CD4+ FOXP3+ cell that suppresses effector cell responses, immune tolerance
B Cell	⌷	ALX/FPR2, GPR32(?)	Antibody production against pathogens, humoral immunity
B regulatory Cell	⌷	BLT1/2	Suppresses expansion of pathogenic lymphocytes, promote Treg generation
γδ T cell	⌷     ⌷	BLT1, EP2, EP4	Immune regulation, inflammation, antigen presentation
Innate Lymphoid Cell Type 1/ Natural Killer Cell	⌷	ALX/FPR2, BLT1, EP1–4	Immunity against intracellular pathogens, cytotoxicity
Innate Lymphoid Cell Type 2	⌷	ALX/FPR2, BLT1, CysLT1R, EP4	Immunity against parasites, allergies and asthma responses
Innate Lymphoid Cell Type 3	⌷	EP4	Immunity against extracellular bacteria, maintains gut homeostasis and mucosal barrier function