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. 2019 Feb 18;79(2):160–176. doi: 10.1055/a-0828-7722
No. Recommendations/Statements GRADE Sources
14.1. Loop excision and laser excision are the methods of choice to treat squamous and glandular cervical intraepithelial neoplasia. ⊕⊖⊖⊖
A
128 ,  129 ,  130
14.2. Cold-knife conization may be used as an alternative to treat glandular intraepithelial neoplasia. ⊕⊖⊖⊖
0
128
14.3. After histological confirmation using punch biopsy, laser vaporization must only be used to treat CIN 1, CIN 2 or CIN 3 if all of the following conditions are met:
  • the whole transformation zone can be visualized (T-Zone Type 1),

  • there are no indications of any changes in the glandular epithelium,

  • there are no indications of any invasive process,

  • there are no discrepancies between cytological, colposcopic and histological assessments of the biology of any changes,

  • the patient is not older than 50 years.

EC