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. 2019 Feb 18;79(2):160–176. doi: 10.1055/a-0828-7722
No. Recommendations/Statements GRADE Sources
14.12. The definitive histopathological diagnosis of ACIS (with the differential diagnosis excluding invasive adenocarcinoma) must be obtained by excision.
Hysterectomy should be the definitive treatment for ACIS if the patient plans to have no more children.
If the patient wishes to have children, R0 resection must be carried out and the patient must be followed up using colposcopy, cytology and HPV testing.
EC