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. 2019 Jan;8(1):19–31. doi: 10.21037/acs.2018.12.02

Table 7. Complications following heparin-induced thrombocytopenia in patients on extracorporeal life support (ECLS).

Variable VA-ECMO (n=15) VV-ECMO (n=13) Total (n=28) P value
Bleeding, n (%) 2 (13.3) 4 (30.8) 6 (21.4) 0.509
Total thrombosis, n (%) 10 (66.7) 5 (38.5) 15 (53.6) 0.266
Thromboembolism, n (%)
   Arterial 8 (53.3) 0 (0.0) 8 (28.6) 0.007
      Ischemic cerebrovascular accident 2 (13.3) 0 (0.0) 2 (7.1) 0.528
      Digital ischemia 2 (13.3) 0 (0.0) 2 (7.1) 0.528
      Upper limb ischemia leading to amputation 1 (6.7) 0 (0.0) 1 (3.6) 1.000
      Axillary artery thrombosis 1 (6.7) 0 (0.0) 1 (3.6) 1.000
      Femoral artery thrombosis 1 (6.7) 0 (0.0) 1 (3.6) 1.000
      Aortic valve thrombosis 1 (6.7) 0 (0.0) 1 (3.6) 1.000
   Venous 5 (33.3) 1 (7.7) 6 (21.4) 0.235
      Deep vein thrombosis, lower limbs 0 (0.0) 1 (7.7) 1 (3.6) 0.942
      Deep vein thrombosis, unspecified 1 (6.7) 0 (0.0) 1 (3.6) 1.000
      Upper limb, unspecified 1 (6.7) 0 (0.0) 1 (3.6) 1.000
      Femoral vein thrombosis 1 (6.7) 0 (0.0) 1 (3.6) 1.000
      Inferior vena cava thrombosis 1 (6.7) 0 (0.0) 1 (3.6) 1.000
   ECLS circuit 2 (13.3) 4 (30.8) 6 (21.4) 0.509
      Oxygenator 0 (0.0) 4 (30.8) 4 (14.3) 0.075
      Unspecified 2 (13.3) 0 (0.0) 2 (7.1) 0.528
ECLS device/circuit exchange, n (%) 2 (13.3) 7 (53.8) 9 (32.1) 0.060

VA, veno-arterial; VV, veno-venous; ECMO, extracorporeal membrane oxygenation; ECLS, extracorporeal life support.