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. 2018 Oct;28(10):1059–1088. doi: 10.1016/j.euroneuro.2018.08.001

Table 1.

Reported effect sizes (standardised mean difference) from meta-analysis for studies of treatment efficacy for ADHD core symptoms in childhood and adulthood.

Treatment and age-group Treatment type Effect size Reference
Childhood: pharmacological treatment Methylphenidate 0.72 Faraone and Buitelaar (2010)
Amphetamines 0.99 Faraone and Buitelaar (2010)
Atomoxetine 0.64 Schwartz and Correll (2014)
Guanfacine 0.63 Hirota et al. (2014)
Clonidine 0.44 Hirota et al. (2014)
Childhood: non-pharmacological treatment Omega-3 0.16 Sonuga-Barke et al. (2013)
Diets 0.42 Sonuga-Barke et al. (2013)
Neurofeedback 0.21 Hodgson et al. (2014)
Multimodal psychosocial 0.09 Hodgson et al. (2014)
Working memory training −0.02−0.20 Cortese et al. (2015); Hodgson et al. (2014)
Behaviour modification −0.03 Hodgson et al. (2014)
Parent training −0.51 Hodgson et al. (2014)
Self-monitoring −5.91 Hodgson et al. (2014)
School-based −0.26−0.16 Hodgson et al. (2014); Richardson et al. (2015)
Adulthood: pharmacological treatment Methylphenidate 0.42−0.72 Castells et al., 2011b, Epstein et al., 2014
Amphetamines 0.72−1.07 Castells et al. (2011a); Fridman et al. (2015)
Atomoxetine 0.38−0.60 Asherson et al. (2014); Fridman et al. (2015)
Adulthood: non-pharmacological treatment Cognitive-behavioural therapy 0.43−1.0 Jensen et al. (2016); Knouse et al. (2017); Young et al. (2016)
Mindfulness-based therapies 0.53−0.66 Cairncross and Miller (2016)