Figure 8.

Evaluation of the antiviral properties of Sephin1 against myxoma virus. (A) RK13 cells were infected with myxoma virus and incubated in the presence of 50 μM Sephin1 or DMSO alone (control). Viral titers were determined from crude lysates harvested at the indicated times post-infection. (B) Viability of RK13 cells incubated with increasing doses of Sephin1 or DMSO alone was determined after 24 h incubation using the cellular viability assay Vita-Blue. Data represent mean ± SEM from representative experiments, repeated at least three times. ^**p < 0.001, ^***p < 0.001 by one-way analysis of variance, followed by Bonferroni comparison test comparing the Sephin1-treated groups at the indicated concentrations to the vehicle-treated control group.