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. 2019 Feb 18;9:2193. doi: 10.1038/s41598-019-38668-7

Figure 3.

Figure 3

FRET imaging of compound induced conformational change of FXR. Ratio of measured fluorescence intensity of fluorophores cerulean (donor) and citrine (acceptor) plotted in time during administration of 10 μM compound (t = 110 s) and 5 μM GW4064 (t = 230 s), n = 6.