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. 2019 Feb 18;9:2175. doi: 10.1038/s41598-019-38628-1

Table 2.

Variations of the expression of genes involved in glycolysis, TCA cycle and formation of acetyl-coA.

Name Product Gene size RNA-seq values (minimal medium) RNA-seq values (bile salts) Fold change Fold change p value
(bp) RPKM RPKM (Log2)
aceE Pyruvate dehydrogenase E1 2663 6420 11797 −1.8 −0.88 1.188E-02
aceF Dihydrolipoyllysine-residue acetyltransferase 1892 2620 3886 −1.5 −0.57 6.618E-02
ackA acetate kinase 1202 2740 4056 −1.5 −0.57 7.020E-02
acs acetyl-coenzyme A synthetase 1958 2188 837 2.6 1.39 1.897E-04
eno Enolase 1298 9777 15019 −1.5 −0.62 6.921E-02
fbaA Fructose-bisphosphate aldolase class 2 1079 3314 3828 −1.2 −0.21 4.847E-01
fbaB Fructose-bisphosphate aldolase class 1 1124 943 837 1.1 0.17 4.857E-01
fbp Fructose-1.6-bisphosphatase 998 3314 5750 −1.7 −0.79 1.384E-02
fumA Fumarate hydratase class I. aerobic 1646 7038 9348 −1.3 −0.41 1.869E-01
fumB Fumarate hydratase class I. anaerobic 1646 771 415 1.9 0.90 5.607E-05
fumC Fumarate hydratase class II 1403 1122 884 1.3 0.34 1.468E-01
gapA glyceraldehyde-3-phosphate dehydrogenase A 995 25736 36899 −1.4 −0.52 1.405E-01
glk glucokinase 965 832 912 −1.1 −0.13 6.037E-01
gltA Citrate synthase 1283 7479 15175 −2.0 −1.02 7.423E-04
gpmA bisphosphoglycerate-dependent phosphoglycerate 752 10216 19188 −1.9 −0.91 4.772E-03
gpmM bisphosphoglycerate-independent phosphoglycerate 1544 1282 1810 −1.4 −0.50 7.967E-02
icd Isocitrate dehydrogenase [NadP] 1250 17987 30473 −1.7 −0.76 1.944E-02
lpd Dihydrolipoyl dehydrogenase 1424 10039 20656 −2.1 −1.04 1.135E-03
mdh Malate dehydrogenase 938 5402 8506 −1.6 −0.66 2.854E-02
pfkA 6-phosphofructokinase isozyme 1 962 1283 4244 −3.3 −1.72 1.369E-11
pgi glucose-6-phosphate isomerase 1649 4480 5251 −1.2 −0.23 4.652E-01
pgk Phosphoglycerate kinase 1163 2762 4408 −1.6 −0.67 3.299E-02
pta Phosphate acetyltransferase 2144 1355 1764 −1.3 −0.38 1.523E-01
pykA Pyruvate kinase II 1442 1163 1360 −1.2 −0.23 3.798E-01
pykF Pyruvate kinase I 1412 2019 5004 −2.5 −1.31 7.772E-07
sdhA Succinate dehydrogenase flavoprotein subunit 1766 8036 14377 −1.8 −0.84 1.123E-02
sdhB Succinate dehydrogenase iron-sulfur subunit 716 4221 6984 −1.7 −0.73 2.521E-02
sdhC Succinate dehydrogenase cytochrome b556 subunit 389 4494 8916 −2.0 −0.99 1.946E-03
sdhD Succinate dehydrogenase hydrophobic membrane 347 2126 3986 −1.9 −0.91 6.527E-04
sucA 2-oxoglutarate dehydrogenase E1 component 2801 18453 38038 −2.1 −1.04 1.922E-03
sucB Dihydrolipoyllysine-residue succinyltransferase 1217 9625 19122 −2.0 −0.99 5.780E-03
sucC Succinyl-CoA synthetase beta chain 1168 7109 12688 −1.8 −0.84 1.840E-02
sucD Succinyl-CoA ligase [adP-forming] subunit α 869 9683 12034 −1.2 −0.31 3.924E-01
tpiA Triosephosphate isomerase 767 4649 4399 1.1 0.08 8.098E-01

1Values shown in bold are significant.