Fig. 5.

Treatment with NP-[CPP]-doxo in mouse CNV model. a Cumulative doxorubicin release (as % of total amount loaded) from NP-[CPP]-doxo at 37 °C in vitro by dialysis, with or without irradiation (400 nm LED for 1 min at 50 mW cm⁻²) at t = 0. Data are means ± SD (n = 4 independent experiments). b Representative isolectin GS IB₄-stained CNV images (the scale bar is 100 μm) and mean CNV lesion area from laser-induced CNV mice treated with PBS, NP-[CPP], doxo, NP-[CPP]-doxo, and NP-[CPP]-doxo with irradiation. Error bars show standard error of the mean. n = 28 lesions. *P < 0.05, **P < 0.005 (unpaired t-test). (See Supplementary Fig. 14 for graph of individual data points and Supplementary Table 1 for the standard deviations.)