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. 2019 Feb 19;39(2):BSR20181031. doi: 10.1042/BSR20181031

Table 2. Logistic regression analysis of associations between SAA1 gene polymorphisms and risk of osteoporosis.

Genotype Cases (n=300) Controls (n=350) OR (95% CI) P
n % n %
Rs183978373
CC 225 75.0 245 70.0 1.00
CA 65 21.7 97 27.7 0.73 (0.51, 1.05) 0.088
AA 10 3.3 8 2.3 1.36 (0.53, 3.51) 0.524
AA+CA 75 25.0 105 30.0 0.78 (0.55, 1.10) 0.156
CC+CA 290 96.7 342 97.7 1.00
AA 10 3.3 8 2.3 1.47 (0.57, 3.78) 0.420
C allele 515 85.8 587 83.9 1.00
A allele 85 14.2 113 16.1 0.86 (0.63, 1.16) 0.323
Rs12218
TT 98 32.7 113 32.3 1.00
TC 137 45.7 187 53.4 0.85 (0.60–1.20) 0.343
CC 65 21.7 50 14.3 1.50 (0.95–2.37) 0.083
TC+CC 202 67.3 237 67.7 0.98 (0.70–1.36) 0.918
TT+TC 235 78.4 300 85.7 1.00
CC 65 21.7 50 14.3 1.66 (1.11–2.49) 0.015
T allele 333 44.5 413 59.0 1.00
C allele 267 55.4 287 41.0 1.15 (0.93–1.44) 0.203
Rs10832915
TT 108 36.0 148 42.3 1.00
TC 140 46.7 158 45.1 1.21 (0.87, 1.70) 0.258
CC 52 17.3 44 12.6 1.62 (1.01, 2.60) 0.045
TC+CC 192 64.0 202 57.7 1.30 (0.95, 1.79) 0.102
TT+TC 248 82.7 306 87.4 1.00
CC 52 17.3 44 12.6 1.46 (0.94, 2.25) 0.089
T allele 356 40.7 554 64.9 1.00
C allele 244 59.3 246 35.1 1.26 (1.01, 1.58) 0.041

Bold values are statistically significant (P<0.05).