Table 3.

Genotype and allele frequencies of DRD2 SNPs in control male subjects and schizophrenia male patients

SNP	Case		Control		p‐Value	OR	95% CI	Power
	N	%	N	%
Rs7116768					0.037
G/G	131	85.06	132	84.08
G/C	14	9.10	23	14.65
C/C	9	5.84	2	1.27
G/G + G/C	145	94.16	155	98.73	0.034	0.208	0.044–0.978	0.586
C allele	32	10.39	54	8.60	0.015	1.791	1.121–2.863	0.625
Rs1047479195					0.576
C/C	143	92.86	150	95.54
C/A	9	5.84	5	3.18
A/A	2	1.30	2	1.27
A/A + C/A	11	7.14	7	4.46	0.341	1.648	0.622–4.370	0.180
A allele	13	4.22	9	2.87	0.392	0.670	0.282–1.590	0.117
Rs1799732					0.075
Ins/Ins	131	85.06	132	84.08
Ins/Del	15	9.74	23	14.65
Del/Del	8	5.19	2	1.27
Ins/Ins + Ins/Del	146	94.81	155	98.73	0.059	0.235	0.049–1.127	0.500
Del allele	64	10.06	54	8.60	0.262	0.792	0.530–1.184	0.121
Rs1799978					0.120
A/A	109	70.78	104	66.24
G/A	36	23.38	39	24.84
G/G	9	5.84	14	8.92
A/A + G/A	145	94.16	143	92.86	0.387	1.577	0.662–3.760	0.153
G allele	54	17.53	67	21.34	0.265	1.276	0.856–1.901	0.251

The SNPs with minor allele frequency <0.01 were excluded. The p‐value was calculated by 2 × 3 and 2 × 2 chi‐square test, in which the codominant model, the recessive model, and the allele model were corrected by Bonferroni's correction and the p < 0.05/4was statistically significant. The statistical power is considered to be enough when power >0.8. The false discovery rate <0.05.