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. 2019 Jan 4;13(2):176–183. doi: 10.1111/irv.12615

Table 2.

Effectiveness of vitamin D supplementation on reducing RT‐PCR–confirmed influenza and non‐influenza respiratory infections

Outcome RT‐PCR–confirmed infection HRa (95% CI)
Vitamin D Placebo
Non‐influenza virus infection
All Years 146/650 (22.5%) 185/650 (28.5%) 0.76 (0.61‐0.94)
Year 1 54/200 (27.0%) 75/200 (37.50%) 0.65 (0.46‐0.93)
Year 2 92/450 (20.4%) 110/450 (24.4%) 0.82 (0.62‐1.08)
Influenza virus infection
All Years 50/650 (7.7%) 43/650 (6.6%) 1.18 (0.79‐1.77)
Year 1 25/200 (12.5%) 29/200 (14.5%) 0.85 (0.50‐1.46)
Year 2 25/450 (5.6%) 14/450 (3.1%) 1.82 (0.95‐3.52)
All viral infections
All Years 177/650 (27.2%) 209/650 (32.2%) 0.81 (0.67‐0.99)
Year 1 72/200 (36.0%) 90/200 (45.0%) 0.73 (0.53‐0.99)
Year 2 105/450 (23.3%) 119/450 (26.4%) 0.87 (0.67‐1.13)
a

All hazard ratios were calculated using the participants’ first infection with the virus.