Table 1.
DNA sequences used in this study
| Type | Name | Sequence (5′-3′)* |
|---|---|---|
| Oxytricha telomeric sequences | Otel3Δ2 | GGTTTTGGGGTTTTGGGG |
| Otel3 | GGGGTTTTGGGGTTTTGGGG | |
| P1 | TTGGGGTT | |
| P2 | TGGGGTT | |
| P3 | TTGGGGT | |
| P4 | TGGGG | |
| P5 | GGGGT | |
| P6 | TGGGGA | |
| Human telomeric sequences | htel3Δ1 | GGTTAGGGTTAGGG |
| htel3Δ1-Ino11 | GGTTAGGGTTIGGG | |
| htel3Δ1-G11 | GGTTAGGGTTGGGG | |
| htel1 | TTAGGG | |
| Inosine substitution | Otel3Δ2-Ino1 | IGTTTTGGGGTTTTGGGG |
| Otel3Δ2-Ino2 | GITTTTGGGGTTTTGGGG | |
| Otel3Δ2-Ino7 | GGTTTTIGGGTTTTGGGG | |
| Otel3Δ2-Ino8 | GGTTTTGIGGTTTTGGGG | |
| Otel3Δ2-Ino9 | GGTTTTGGIGTTTTGGGG | |
| Otel3Δ2-Ino10 | GGTTTTGGGITTTTGGGG | |
| Otel3Δ2-Ino15 | GGTTTTGGGGTTTTIGGG | |
| Otel3Δ2-Ino16 | GGTTTTGGGGTTTTGIGG | |
| Otel3Δ2-Ino17 | GGTTTTGGGGTTTTGGIG | |
| Otel3Δ2-Ino18 | GGTTTTGGGGTTTTGGGI | |
| P6-Ino20 | TIGGGA | |
| P6-Ino21 | TGIGGA | |
| P6-Ino22 | TGGIGA | |
| P6-Ino23 | TGGGIA | |
| Uridine substitution | Otel3Δ2-dU4 | GGTdUTTGGGGTTTTGGGG |
| Otel3Δ2-dU6 | GGTTTdUGGGGTTTTGGGG | |
| Otel3Δ2-dU11 | GGTTTTGGGGdUTTTGGGG | |
| Otel3Δ2-dU13 | GGTTTTGGGGTTdUTGGGG | |
| Mutations on Otel3Δ2 or P6 | Otel3Δ2-T15 | GGTTTTGGGGTTTTTGGG |
| Otel3Δ2-T16 | GGTTTTGGGGTTTTGTGG | |
| Otel3Δ2-A16 | GGTTTTGGGGTTTTGAGG | |
| Otel3Δ2-YA | GGTTTTGGGGTTTTGAGGG | |
| Otel3Δ2-Y2A | GGTTTTGGGGTTTTGAAGGG | |
| Otel3Δ2-YT | GGTTTTGGGGTTTTGTGGG | |
| Otel3Δ2-Y2T | GGTTTTGGGGTTTTGTTGGG | |
| Otel3Δ2-XA | AGGTTTTGGGGTTTTGGGG | |
| Otel3Δ2-XT | TGGTTTTGGGGTTTTGGGG | |
| Otel3Δ2-X2T | TTGGTTTTGGGGTTTTGGGG | |
| Otel3Δ2-X3T | TTTGGTTTTGGGGTTTTGGGG | |
| Otel3Δ2-X4T | TTTTGGTTTTGGGGTTTTGGGG | |
| Otel3Δ2-T7 | GGTTTTTGGGTTTTGGGG | |
| Otel3Δ2-D7 | GGTTTTGGGTTTTGGGG | |
| P6-T20 | TTGGGA | |
| Complementary chains | C3Δ2 | CCCCAAAACCCCAAAACC |
| C3 | CCCCAAAACCCCAAAACCCC |
*I and dU refer to an inosine and a uridine, respectively.