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. 2019 Feb 12;10:112. doi: 10.3389/fmicb.2019.00112

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Copyright © 2019 Carreté, Ksiezopolska, Gómez-Molero, Angoulvant, Bader, Fairhead and Gabaldón.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Single nucleotide polymorphisms (SNPs)/Kb between genomes of matched pairs of isolates. (A) Amount of different SNPs/Kb between each compared pair of genomes. Gray bar indicates the average of between all pairs of non-clonal strains from a previous study (Carreté et al., 2018). (B) Correlation between genome-wide mutation density (SNPs/Kb) and days span between the first isolate and second isolate in serial isolates. Yellow dots indicate pairs of strains isolated at the same day from different sites. Blue dots and triangles indicate pairs of strains isolated at different days at different sites or the same site, respectively. Blue line shows linear regression over the blue values.