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. 2019 Feb 12;10:112. doi: 10.3389/fmicb.2019.00112

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Copyright © 2019 Carreté, Ksiezopolska, Gómez-Molero, Angoulvant, Bader, Fairhead and Gabaldón.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Structural genomic variation in clonal isolates. (A) Aneuploidy found in chromosomes C and E in CMRL2. Chromosome A as a control without any aneuploidy. Y-axis show the distribution of depth of coverage (density) per each chromosome. Vertical dashed line in X-axis indicates the threshold used to detect chromosome duplications (threshold 1.8). Chromosomes affected are marked with arrows. (B) Heatmap showing deleted and duplicated genes that appeared in only one of the two isolates of a pair. Gene name in bold indicates genes related to cell-wall proteins or adhesines.