Figure 2.

Signal structure at the strong gyrase binding site from bacteriophage Mu (Mu SGS). (A) Profiles of the number of 5′- and 3′-ends (N5E and N3E correspondingly) are shown in black. Total coverage depth (Depth) is in blue and coverages for DNA fragments that were aligned in forward and reverse orientations (F DNAs and R DNAs correspondingly) are in red and sky blue respectively. Tracks height (depth) are shown in brackets. The data visualized in IGV (58). (B) Close-up of the cleavage site. Coverage depth around the site is shown as a grey track, local sequence lies below. Cleavage sites known from the existing literature are shown (31,45,46).