Table II. List of Abs derived from different B cell subsets and their binding to different Ags.
Origin B Cell Subset | FACS Phenotype | Name of Ig | LC | As IgM-BCR | As IgG Ab | Reference | ||||
---|---|---|---|---|---|---|---|---|---|---|
Sm | LPS | dsDNA | LPS | Insulin | Hep-2 | |||||
B1 | CD19+CD20+ | B1-9 | λ | + | + | + | + | + | + | Described in this article |
CD27+CD43+ | B1-36 | κ | + | − | + | + | + | + | Described in this article | |
CD70− | B1-72 | λ | − | − | − | − | − | + | Described in this article | |
B1-76 | κ | − | − | − | − | − | + | Described in this article | ||
ne | CD19+CD10+ | ne-GO18 | λ | − | − | − | − | − | − | Wardemann et al., 2003 (4) |
IgM+CD27− | ne-GO51 | κ | − | − | − | − | − | + | Wardemann et al., 2003 (4) | |
ne-GO77 | κ | − | − | + | + | + | + | Wardemann et al., 2003 (4) | ||
ne-GO78 | κ | − | − | − | − | − | − | Wardemann et al., 2003 (4) | ||
m naive | CD19+CD10−IgM+CD27− | m-JH.2A8 | κ | − | − | + | + | + | + | Wardemann et al., 2003 (4) |
m-JH.2F9 | κ | − | − | − | − | − | Wardemann et al., 2003 (4) | |||
m-GO16 | κ | − | − | + | + | + | − | Wardemann et al., 2003 (4) | ||
m-GO43 | κ | − | − | − | − | − | + | Wardemann et al., 2003 (4) | ||
m-GO53 | κ | − | − | − | − | − | − | Wardemann et al., 2003 (4) | ||
m-GO56 | κ | − | − | − | − | − | − | Wardemann et al., 2003 (4) | ||
IgM+ memory | CD19+CD10−IgM+CD27+ | mm5-GO44 | λ | − | − | − | − | − | − | Tsuiji et al., 2006 (23) |
mm-GO9 | λ | − | − | + | + | + | − | Tsuiji et al., 2006 (23) | ||
mm-GO30 | κ | + | + | − | − | − | − | Tsuiji et al., 2006 (23) | ||
mm-JB57 | κ | − | − | − | − | − | − | Tsuiji et al., 2006 (23) |
and − represent positive and negative for Ag binding, respectively.