Table 3.

Additional information on primary outcomes

	Pre-intervention		Post-intervention		Planned adjusted comparison (trend and step)*	Adjusted comparison (bent stick)*
	n/N (%)	Rate per 10 000 deliveries	n/N (%)	Rate per 10 000 deliveries
Place of death (as % of all deaths)
Central referral facility	428/451 (94·9%)	..	522/546 (95·6%)	..	..	..
Peripheral facility	12/451 (2·7%)	..	17/546 (3·1%)	..	..	..
Community	11/451 (2·4%)	..	7/546 (1·3%)	..	..	..
Cause of death
Obstetric haemorrhage	147/451 (32·6%)	6·0	212/546 (38·8%)	7·3	0·86 (0·56–1·33)	0·56 (0·29–1·05)
Pregnancy-related sepsis	67/451 (14·9%)	2·7	74/546 (13·6%)	2·6	..	..
Other sepsis	15/451 (3·3%)	0·6	13/546 (2·4%)	0·5	..	..
Hypertensive disorder in pregnancy (eclampsia, pre-eclampsia, or stroke)	81/451 (18·0%)	3·3	123/546 (22·5%)	4·3	0·76 (0·46–1·25)	2·07 (0·33–13·12)
Other	141/451 (31·3%)	5·7	125/546 (22·9%)	4·3	0·88 (0·62–1·24)	0·54 (0·05–5·73)
Place of first eclamptic fit
Central referral facility	506/1314 (38·5%)	20·5	333/1378 (24·2%)	11·5	0·56 (0·33–0·97)	1·17 (0·53–2·55)
Peripheral facility	280/1314 (21·3%)	11·3	363/1378 (26·3%)	12·6	1·55 (1·10–2·20)	1·35 (0·17–10·45)
Community	528/1314 (40·2%)	21·4	682/1378 (49·5%)	23·6	1·02 (0·56–1·86)	2·78 (0·65–11·89)
Cause of hysterectomy
Postpartum haemorrhage	112/316 (35·4%)	4·5	148/365 (40·5%)	5·1	1·23 (0·72–2·10)	0·45 (0·11–1·09)
Ruptured uterus	151/316 (47·8%)	6·1	172/365 (47·1%)	6·0	0·87 (0·41–1·84)	0·12 (0·02–0·82)
Sepsis	21/316 (6·6%)	0·8	25/365 (6·8%)	0·9	..	..
Other	32/316 (10·1%)	1·3	20/365 (5·5%)	0·7	..	..

Data are n/N (%) or odds ratio (95% CI) unless otherwise stated.

^*Adjusted for cluster effect, time from start of study (with an interaction between cluster and time so that each cluster had its own underlying time trend), and total time on the randomised intervention.