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. 2019 Feb 12;10:6. doi: 10.3389/fphys.2019.00006

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Copyright © 2019 Kus, Kaczara, Czyzynska-Cichon, Szafranska, Zapotoczny, Kij, Sowinska, Kotlinowski, Mateuszuk, Czarnowska, Szymonski and Chlopicki.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Fasting glucose concentration and GTT with calculated AUC of the GTT (A). Representative images of liver steatosis (ORO staining) (B), immune cells infiltration (HE staining) (C) and fibrosis (Picro Sirius Red staining) (D) and summary results of liver steatosis (B), performed in C57Bl/6 mice at early and late stage of NAFLD progression. Values are means ± SD. ^∗P < 0.05, ^∗∗P < 0.01, ^∗∗∗P < 0.001 significantly different from HFD feeding time-matched AIN-93G group values. AIN-93G, AIN-93G diet fed group; HFD, high fat diet fed group.