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. 2019 Feb 5;2019:2457082. doi: 10.1155/2019/2457082

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Copyright © 2019 Chunyang Zhang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Protective effect of HUMSCs on RILI. (a) Compared to control HUMSCs, CXCR4-overexpressing HUMSCs could attenuate histopathological changes of RILI by hematoxylin and eosin (H&E) and Masson staining of lung sections. (b) TGF-β1 protein was assessed by western blot analysis in the mouse lung tissue. (c) Densitometric quantification of TGF-β1 protein levels in the lung tissue. The radiation-induced enhancement of TGF-β1 was inhibited markedly in the CXCR4-overexpressing group compared to control group (^∗∗ P < 0.01, n = 6).