Table 1.
The top ten up- and downregulated DEGs between Parkinson's disease and healthy controls.
| Upregulated DEGs | Downregulated DEGs | ||||
|---|---|---|---|---|---|
| DEGs | Log FC | P value | DEGs | Log FC | P value |
| RPS4Y1 | 1.436363 | 0.015519 | DLG1 | −1.26172 | 0.000313 |
| DDX3Y | 1.29367 | 0.022047 | PURG | −1.08174 | 0.003411 |
| PRKAG2 | 1.148714 | 0.00055 | HLA-DQB1 | −0.99125 | 0.00143 |
| GLRA3 | 1.049017 | 0.001367 | PDE6D | −0.98539 | 0.000514 |
| PCDH7 | 1.042698 | 0.007899 | ABCD2 | −0.98339 | 0.006745 |
| EMP1 | 1.032737 | 0.003364 | ATP8A1 | −0.97496 | 0.002029 |
| MAGEA2B | 1.000555 | 0.007728 | ZFAND1 | −0.96026 | 0.003311 |
| KRT20 | 0.97463 | 0.006048 | IFI27 | −0.95815 | 0.002065 |
| GPR68 | 0.972924 | 0.000615 | SDHAF3 | −0.94893 | 0.007156 |
| DCT | 0.960358 | 0.001683 | PTPN20 | −0.94006 | 0.033347 |
DEGs: differentially expressed genes; log FC: log fold-change.