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. 2019 Feb 18;12:92. doi: 10.1186/s13104-019-4111-9

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Representative time course of hOGG1 activity. One strand of this 20 bp duplex contains 8oxoG at the 10th position from the radiolabeled 5′ end. The substrate was incubated with hOGG1, in this case wild-type, for the time indicated, quenched with hot alkali, and then analyzed by denaturing polyacrylamide gel electrophoresis. The 20-mer band corresponds to non-cleaved DNA, while the 9-mer band corresponds to DNA processed by hOGG1