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. 2019 Feb 19;18:27. doi: 10.1186/s12943-019-0951-0

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Overexpression of cTFRC induces BC cell proliferation and invasion. a, b Proliferation of EJ and T24 cells transfected with cTFRC vector assessed using ³H-TdR incorporation at the indicated days. c Determination of cell invasive potential of EJ and T24 cells transfected with cTFRC vector by transwell assay. d, e Proliferation of EJ and T24 cells transfected with shCtrl, shcTFRC-1 or shcTFRC-1 + oe-cTFRC. f, g Transwell assays were used to evaluate the invasion in EJ and T24 cells after transfection with shCtrl, shcTFRC-1 or shcTFRC-1 + oe-cTFRC. Data are the means ± SD of three independent experiments. **P < 0.01