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. 2019 Feb 18;16:13. doi: 10.1186/s12986-019-0339-6

Fig. 2.

Fig. 2

Hepatic iron overload is dependent on genetic background. Representative images of liver stained with Perls’ Prussian Blue from LG/J mice fed the control iron diet (a) and high iron diet (b), and SM/J mice fed control iron diet (c) and high iron diet (d). High iron-fed LG/J mice experience dramatic increase in total hepatic iron deposition (e), which coincides with increased serum ferritin (f). Panel E: n = 9–15 mice per strain X diet cohort. Panel F: n = 12–15 mice per strain X diet cohort. Panels E, F – *p-value < 0.05, **p-value < 0.01, ***p-value < 0.001 assessed by ANOVA with Tukey’s Post Hoc Correction. N.S. – Not significant. Error bars represent standard deviation