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Superposition of TbRRP44-NPIN and ScRrp44 structures in two functional conformations. TbRRP44-NPIN is shown in orange. The ScRrp44 coordinates are from PDB 5K36 and 4IFD, corresponding to the direct route (a) and channel route (b) conformations, respectively. ScRrp44 is colored by domain. NPIN is shown in blue. CSD, RNB and S1 domains are represented in light pink, magenta and dark purple, respectively. TbRRP44 helix α6 and ScRrp44 Pro226 are indicated.
