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. 2019 Feb 11;10(1):21–32. doi: 10.1080/19491034.2019.1578600

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© 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Genomic profiling of dis3^E729K and dis3-ts indicates potential mitotic defects. (a) Overall results showing negative genetic interactions from two screens in this study, and the published dis3-1 SGA screen [20]. (b) Analysis of gene ontology terms among three gene lists reveals specialization of DIS3 mutant allele phenotypes. (c) Spot-dilution assay validations of negative genetic interactions between spc24 or dam1 mutant alleles with dis3^E729K.