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. 2018 Dec 10;11(2):350–372. doi: 10.1080/19420862.2018.1551044

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© 2018 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 12. — Static light scattering analysis to measure aggregation propensity by temperature ramping showed aggregation temperature was increased by terminal galactosylation and decreased by terminal sialylation. (a) SLS counts of each glycoform. (b) Aggregation temperatures (T_agg) showed increased stability by terminal galactosylation and decreased stability by terminal sialylation. Core defucosylation also showed slightly decreased T_agg. Error bars represent variation range of n = 2.