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. 2019 Feb 19;15(2):e8636. doi: 10.15252/msb.20188636

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© 2019 The Authors. Published under the terms of the CC BY 4.0 license

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Figure EV1 — A
Heatmap showing Spearman correlation coefficients between physiological parameters across 3,564 conditions.

B–E
Scatter plots of four parameter pairs across 3,564 samples. Note that each parameter of each treatment was normalized by subtracting control vehicle treatments and divided by interquartile range IQR across all 3,564 conditions. (B) Example of strong positive correlation: Ht and Hb. (C) Comparison of two liver injury markers: ALT and DBIL. (D) Comparison of two kidney injury markers: BUN and CRE. (E) Example of strong negative correlation: Neu and Lym.