Table 5.
Risk of breast cancer and history of hypertension (HBP), high cholesterol, and diabetes by body mass index (BMI, kg/m2) and waist circumference (cm) in postmenopausal Asian American women in Los Angeles County
| BMI ≤ 24.91 | BMI > 24.91 | Waist ≤ 86 cm | Waist > 86 cm | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ca | Co | OR2 (95%CI) | Ca | Co | OR2(95%CI) | Ca | Co | OR2 (95%CI) | Ca | Co | OR2 (95%CI) | |
| HPB | ||||||||||||
| No | 525 | 457 | 1 | 149 | 120 | 1 | 510 | 450 | 1 | 164 | 127 | 1 |
| Yes | 287 | 214 | 1.08 (0.86, 1.37) | 217 | 124 | 1.42 (0.98, 2.06) | 277 | 205 | 1.12 (0.88, 1.42) | 227 | 133 | 1.31 (0.92, 1.86 |
| P interaction | 0.28 | 0.38 | ||||||||||
| High Cholesterol | ||||||||||||
| No | 501 | 456 | 1.00 | 237 | 171 | 1 | 486 | 446 | 1.00 | 229 | 174 | 1 |
| Yes | 335 | 222 | 1.37 (1.09, 1.73) | 141 | 78 | 1.21 (0.82, 1.78) | 300 | 208 | 1.35 (1.07, 1.71) | 162 | 86 | 1.42 (0.98, 2.05) |
| P interaction | 0.82 | 0.88 | ||||||||||
| Diabetes | ||||||||||||
| No | 727 | 625 | 1.00 | 293 | 195 | 1 | 707 | 611 | 1.00 | 313 | 209 | 1 |
| Yes | 85 | 46 | 1.62 (1.09, 2.41) | 73 | 49 | 0.89 (0.56,1.40) | 73 | 44 | 1.61 (1.07, 2.42) | 78 | 51 | 1.10 (0.71, 1.70) |
| P interaction | 0.097 | 0.18 | ||||||||||
| Any 3 Conditions | ||||||||||||
| No | 325 | 323 | 1.00 | 98 | 81 | 1 | 322 | 319 | 1.00 | 101 | 85 | 1.00 |
| Yes | 487 | 348 | 1.40 (1.12, 1.75) | 268 | 163 | 1.30 (0.87, 1.95) | 465 | 336 | 1.39 (1.10, 1.74) | 290 | 175 | 1.43 (0.97, 2.10) |
| P interaction | 0.72 | 0.87 | ||||||||||
1
We excluded 37 cases and 13 control women who had data on BMI but did not have information on waist circumferences in the above analyses. All the above stratified results by BMI remained largely the same when we included these 37 cases and 13 control women in the analyses.
2
Adjusted for Asian ethnicity, age, education, income, years of residence in the US among non-US born, interviewer, family history of breast cancer, benign breast diseases, parity, age at menarche, education, and age and type of menopause.