Figure 1:

Locuszoom plots of the MAP2K5 locus using discovery results for established loci that reached genome-wide significance for BMI in men and women combined in the AAAGC [23•]. Plots use EUR and AFR LD from the 1000 Genomes phase 1 reference panel. In each plot, the most significant variant in AAAGC within a 1Mb regional locus is highlighted. P-values for all variants including the most significant variant are based on the African ancestry discovery phase only. (Reproduced from Ng MCY, Graff M, Lu Y, et al (2017) Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium. PLoS Genet 13:e1006719. This work is made available under the Creative Commons CC0 public domain dedication) [23••].