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. 2019 Feb 19;14(2):e0212259. doi: 10.1371/journal.pone.0212259

Table 1. Characteristics of 286,680 oral glucocorticoid users according to sex, age, glucocorticoid type, dose, and morbidity as of the date of cessation.

Characteristics Number (%)
Sex
Female 163,077 (57)
    Male 123,603 (43)
Age, years
0–19 4,188 (1.5)
    20–39 21,806 (7.6)
    40–59 55,894 (20)
    60–79 140,056 (49)
    ≥80 64,736 (23)
Type of glucocorticoid use (last prescription)
Betamethasone 68 (0.02)
Dexamethasone 215 (0.07)
Methylprednisolone 6,126 (2.1)
Prednisolone 280,010 (98)
Prednisone 0 (0)
Hydrocortisone 261 (0.09)
Cumulative dose a
< 0.5 g 21,114 (7.4)
0.5–5 g 171,566 (60)
5+ g 94,000 (33)
Average daily dose a
    < 5 mg /day 86,099 (30)
5–9 mg/day 114,194 (40)
10–20 mg/day 57,970 (20)
20 + mg/day 28,417 (9.9)
Morbidity
Polymyalgia rheumatica/ giant cell arteritis 28,220 (9.8)
Rheumatoid arthritis 21,256 (7.4)
Psoriasis arthritis 1,943 (0.68)
Ankylosing spondylitis 881 (0.31)
Other rheumatological diseases 9,129 (3.2)
Other autoimmune diseases 1,900 (0.66)
Renal diseases 12,568 (4.4)
Cancer 64,503 (23)
Dermatological diseases 1,851 (0.65)
Ulcerative colitis 10,841 (3.8)
Crohn’s disease 6,264 (2.2)
Ashma 29,573 (10)
COPD 63,685 (22)
Multiple sclerosis 1,656 (0.58)
Concomitant glucocorticoid treatmentb
Locally acting (inhaled, acting on the intestine, or topical) 90,937 (32)
Injections 15,971 (5.6)

a In prednisolone equivalents.

b Defined as prescription redemption throughout the observation period.