Table 1. Characteristics of 286,680 oral glucocorticoid users according to sex, age, glucocorticoid type, dose, and morbidity as of the date of cessation.
Characteristics | Number (%) |
---|---|
Sex | |
Female | 163,077 (57) |
Male | 123,603 (43) |
Age, years | |
0–19 | 4,188 (1.5) |
20–39 | 21,806 (7.6) |
40–59 | 55,894 (20) |
60–79 | 140,056 (49) |
≥80 | 64,736 (23) |
Type of glucocorticoid use (last prescription) | |
Betamethasone | 68 (0.02) |
Dexamethasone | 215 (0.07) |
Methylprednisolone | 6,126 (2.1) |
Prednisolone | 280,010 (98) |
Prednisone | 0 (0) |
Hydrocortisone | 261 (0.09) |
Cumulative dose a | |
< 0.5 g | 21,114 (7.4) |
0.5–5 g | 171,566 (60) |
5+ g | 94,000 (33) |
Average daily dose a | |
< 5 mg /day | 86,099 (30) |
5–9 mg/day | 114,194 (40) |
10–20 mg/day | 57,970 (20) |
20 + mg/day | 28,417 (9.9) |
Morbidity | |
Polymyalgia rheumatica/ giant cell arteritis | 28,220 (9.8) |
Rheumatoid arthritis | 21,256 (7.4) |
Psoriasis arthritis | 1,943 (0.68) |
Ankylosing spondylitis | 881 (0.31) |
Other rheumatological diseases | 9,129 (3.2) |
Other autoimmune diseases | 1,900 (0.66) |
Renal diseases | 12,568 (4.4) |
Cancer | 64,503 (23) |
Dermatological diseases | 1,851 (0.65) |
Ulcerative colitis | 10,841 (3.8) |
Crohn’s disease | 6,264 (2.2) |
Ashma | 29,573 (10) |
COPD | 63,685 (22) |
Multiple sclerosis | 1,656 (0.58) |
Concomitant glucocorticoid treatmentb | |
Locally acting (inhaled, acting on the intestine, or topical) | 90,937 (32) |
Injections | 15,971 (5.6) |
a In prednisolone equivalents.
b Defined as prescription redemption throughout the observation period.