Table 2. Incidence rates per 1000 person-years with 95% confidence intervals (CI) (n = 286,680).
| Incidence rates per 1000 person years with 95% CIs | ||||||
|---|---|---|---|---|---|---|
| Reference period | Risk period 0 | Risk period 1 (withdrawal period) |
Risk period 2 | Risk period 3 | Risk period 4 | |
| Hypotension | 0.4 (0.3–0.6) |
0.5 (0.5–0.6) | 0.9 (0.7–1.2) |
0.7 (0.5–1.1) |
0.5 (0.3–0.8) |
0.4 (0.2–0.7) |
| Syncope | 8.8 (8.0–9.7) |
6.1 (5.8–6.3) | 8.6 (7.8–9.5) |
0.7 (6.6–8.3) |
6.7 (5.9–7.6) |
5.6 (4.8–6.6) |
| Cardiovascular collapse |
NA | NA | 0.5 (0.3–0.7) | 0.6 (0.4–0.9) | NA | NA |
| Hyponatremia | 1.7 (1.4–2.1) |
0.9 (0.8–1.0) | 2.4 (2.0–2.9) |
1.4 (1.1–1.9) |
1.1 (0.8–1.6) |
0.8 (0.5–1.2) |
| Gastrointestinal symptoms |
19 (18–21) | 14 (13–14) | 30 (28–31) | 24 (22–36) | 15 (13–16) | 14 (12–15) |
| Hypoglycemia |
NA | NA | 0.2 (0.1–0.4) | 0.3 (0.1–0.7) | NA | NA |
NA: Not applicable.