TABLE I.

Differences between disease progression and pseudoprogression⁸²

Characteristic	Pseudoprogression	Disease progression
Performance status	Improves or is stable	Deteriorates
Systemic symptoms	Might or might not improve	Worsens
Symptoms of tumour enlargement	Might or might not be present	Is present
Baseline tumour burden	Initial increase, followed by response or stabilization	Increase
New lesions	Appear, then remain stable or subsequently respond	Appear and increase in size
Biopsy outcomes	Evidence of immune-cell infiltration	No evidence of immune infiltration