Table 1.

Top Candidate Aggregating Proteins

		Relative Abundance (Log2 Fold Change)			New Protein (Log2 Fold Change)
Entry	Gene names	OCL/YCL	OCR/OCL	ORP/OCL	OCL/YCL	OCR/OCL	ORP/OCL
P41216	Acsl1	5.19	−3.09	−3.02	−1.65	2.88	1.71
P11679	Krt8	3.01	−1.82	−2.95	−6.26	9.08	−2.00
P57780	Actn4	1.53	−2.18	−5.12	−1.83	3.63	1.88
Q8BWF0	Aldh5a1	3.84	2.22	−1.41	−1.42	2.70	−1.89
Q03265	Atp5a1	2.46	1.04	−2.31	−2.00	3.07	2.26
P56480	Atp5b	1.71	1.62	−2.46	−1.75	1.98	1.67
P24270	Cat	3.02	−3.29	−5.10	−1.39	2.46	−1.05
P26041	Msn	2.64	−1.01	−1.48	−3.65	2.44	2.07
Q8VDD5	Myh9	1.22	−1.99	−4.74	−1.59	2.29	1.84
P26039	Tln1	3.03	−1.15	−2.00	−1.23	2.46	1.25

Note: OCL = old control; OCR = old calorie restriction; ORP = old rapamycin; YCL = young calorie restriction. q-value < 0.05 for all OCL/YCL ratio comparisons.