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. Author manuscript; available in PMC: 2020 Feb 19.
Published in final edited form as: Environ Sci Technol. 2019 Feb 8;53(4):2114–2123. doi: 10.1021/acs.est.8b05250

Figure 4. Formation rates of PCB metabolites (analyzed as methylated derivatives) reveal that (A) PCB 91; (B), PCB 95, (C) PCB 132 and (D) PCB 136 are metabolized to OH-PCBs by human CYP2A6, CYP2B6, and CYP2E1.

Figure 4.

Metabolism studies were performed using the following incubation conditions: 50 µM PCB; 5-minute incubation at 37 ºC; 10 pmol/mL P450 content; NADPH regenerating system.40 c Incubation with CYP2E1 for 60 min. d Data are presented as mean ± standard deviation, n = 3.